matty007

When this many celebrties are contracting it, you know it's very widespread. I would say that an estimate of 50,000 may even be very low.

This is going to be a major problem. The ones who can work from home, or have large savings, are very fortunate indeed. Sadly, most can't work from home. How can you ask someone who works in John Lewis to work from home? How can you ask a cleaner to stay at home? The vast majority in this country don't have office jobs that enable them to work from home. And even if they do, many employers won't allow them to, and just shut completely for a time. The cases in this virus will be very high, the strain on the NHS will be high also. The deaths in the elderly will be tragic. But the effect on people's lives financially (debt, bankrupt, homelessness) will arguably be even more damaging than the virus itself.

The vast majority of us will survive this. If we have children, they will be just fine. The virus is a coronavirus that is able to be vaccinated, and if not, herd immunity will be achieved. We will return to normal some time down the road. There you go

As yet, there is no real evidence of this. Like anything, you have to weigh up whether the measure is worth it, and whether it will make a noticable change. In my opinion, school closures will have little effect. It seems to me that not only are children largely unaffected by this virus in terms of symptoms, but most, don't seem to be contracting it at all. You really have to factor that if all these children are withdrawn from school, who will look after them? The parents? What about their jobs? Then you have to make the hypothesis that if indeed it does turn out that they are spreaders and they are withdrawn from school, who will likely be looking after them when they have parents that HAVE to work? Probably grandparents.....yes. I personally see very little benefit to it, and it could possibly do more harm than good.

Dirreah, or the runs, is present in about 4% of cases. So while it is possible you have Covid, it is rather unlikely. Also, from most people I have observed, a runny nose is actually quite a rare presenatation. In my expereince, the cough also remains dry throughout.

Very open, and transparent. I will be the first to admit that their handling of this virus at the beginning, was quite abysmal. In fact, it possibly turned something that maybe could have been contained, into a pandemic. However, I will never fault the Chinese for their studies and medical expertise. They have been incredibly competent at testing for this and observing different treatments and outcomes. The Chinese maybe a little 'shy' with the disclosure of cases at times, but nobody can fault them for their medical practices.

This is irrelevant when you are taking the figures from known cases, and then recording how many die from that number. That 16% is from the ones hospitalized. So out of all the hospitalized cases, 16% died. Now, yes, obviously, if you recorded every single case in the nation and then calculated the death rate of those in that age, it would be MUCH lower than 16%.. But, it needs to be said that 16% mortality from all the ones of that age hospitalized is VERY high indeed.

Not a chance, I'm afraid. Barring a miraclous relentment of the virus, this will be a major issue for NHS. Of likes they probably haven't seen before. This is true regardless of if there is lockdowns or not.

Thankfully, the flu recovers quite qucikly, despite being a cruel mistress when you have it. I had Swine Flu in 2009. Woke up perfectly fine, but was unable to get up and walk by the afternoon. After two days, I was fighting fit again. That is the only positive to Influenza.

To put it in to context, the mortality percentage of those over 70 during the Spanish Flu, was 1.9%. Much higher than normal flu, but many orders of magnitude lower than the 16% of this virus. Now, obviosuly, you are judging cases from a small sample size, so it won't be totally accurate, but it is still deeply concerning.

I have no words for how disturbing and extremely concerning this is. As usual, we see very low mortality in the younger demographic. However, the mortality for those older, is frankly terryfying. In medical terms, to see a CFR (Case Fatality Rate) of 16% in over 80's, is unprecetended in a virus such as this. It is even higher still at 19% for 90 years and older. 9% for 70's bracket is equally as disturbing.

Goodnight everyone.

Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia WWW.AGINGANDDISEASE.ORG A coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak in Wuhan, China. Preventing and reversing the cytokine storm may be the key to save the patients with severe COVID-19 pneumonia. Mesenchymal stem cells (MSCs) have been shown to possess a comprehensive powerful immunomodulatory function. This study aims to investigate whether MSC transplantation improves the outcome of 7 enrolled patients with COVID-19 pneumonia in Beijing YouAn Hospital, China, from Jan 23, 2020 to Feb 16, 2020. The clinical outcomes, as well as changes of inflammatory and immune function levels and adverse effects of 7 enrolled patients were assessed for 14 days after MSC injection. MSCs could cure or significantly improve the functional outcomes of seven patients without observed adverse effects. The pulmonary function and symptoms of these seven patients were significantly improved in 2 days after MSC transplantation. Among them, two common and one severe patient were recovered and discharged in 10 days after treatment. After treatment, the peripheral lymphocytes were increased, the C-reactive protein decreased, and the overactivated cytokine-secreting immune cells CXCR3+CD4+ T cells, CXCR3+CD8+ T cells, and CXCR3+ NK cells disappeared in 3-6 days. In addition, a group of CD14+CD11c+CD11bmid regulatory DC cell population dramatically increased. Meanwhile, the level of TNF-α was significantly decreased, while IL-10 increased in MSC treatment group compared to the placebo control group. Furthermore, the gene expression profile showed MSCs were ACE2- and TMPRSS2- which indicated MSCs are free from COVID-19 infection. Thus, the intravenous transplantation of MSCs was safe and effective for treatment in patients with COVID-19 pneumonia, especially for the patients in critically severe condition.

Pleasure.

Many of the people who have had this, have remarked it as being 'The worst flu imaginable'. If you have a high fever, dry cough, sore throat and particularly shortness of breath, the chances are quite high you have this. What makes this virus difficult to pinpoint however outside clinical testing, is the fact that many can also have very mild symptoms, comparable to a common cold, and in many, even milder. There are varying degrees of severity with this virus, but if someone has shortness of breath and high fever, this makes COVID much more likely than common flu, in my opinion .

What a lovely gesture. If there is one positive to come from this virus, it will be increased community care. Younger people offering to get shopping etc for the elderly (providing they are not infected) will make a MASSIVE diffrenece to the outcome.

We do have to remember that there are MANY viruses already circulating in the population. For most, their symptoms would be indicative of the common cold, or flu, rather than COVID. Even at this stage, the chances of someone contracting COVID is still fairly low, over the whole population. I have been within arms distance of patients with COVID and could tell the diffrence straight away, but many won't. At the end of the day however, it's reached the point that it really is irrelevant. Anyone with a sore throat should isolate.

I'm off now everyone. Have a good Sunday afternoon. Take care.

Can probably x that 7,753 by ten, at the least.

I think sometimes, people get confused with viruses. They see it rising slowly at the start, and can't understand how it can reach millions in a matter of weeks. The R0 is a very scary figure. If you have 20,000 cases, that will turn into 40,000 the following week. Then the next week, it doubles again. Doubling small numbers like 100 is not shock inducing. When you start doubling 100,000, then doubling 200,000... well, it gets very scary.

These case rises are getting sobering now. Viruses are quite slow to gain momentum to start, but once they get to this point, given this doubles every 4 days, it does not take long to reach massive figures.

Indeed. The problem is, many don't. Vitamin D defincency is so common in the UK.

There is going to have to be a price paid. If you go the herd immunity route (which I think is the best way) then if you don't isolate the elderly, you will see many elderly cases, quite a few deaths, and a lot of strain on the NHS. Isolating the elderly ensures that they are at lower risk of contracting the virus from younger people, while also ensuring those younger people obtain immunity over time. In my opinion, it is the best way. Either way, there is going to be sacrifices. The choice is how severe, for how long, and what severity of consequences.

Wow, that is shocking.

The time has passed. N95 masks are preety much impossible to obtain, as oxygen will be. The time for preperation has long gone. Hopefully they will learn from this and make sure to stockpile for a virus of this nature in the future.